Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle

By American Hair Research Society | March 15, 2017

Helen B. Everts, PhD. Vanderbilt University Medical Center, Nashville, TN Vitamin A is essential for the development and maintenance of multiple epithelial tissues, including skin and hair (Frazier and Hu, 1931, Peck and DiGiovanna, 1994, Wolbach and Howe, 1925). The skin takes up circulating retinol and can either store it in the form of retinyl esters or metabolize it to retinoic acid (RA,…

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